Glycan Engineering for Cell and Developmental Biology
نویسندگان
چکیده
منابع مشابه
Developmental biology and tissue engineering.
Morphogenesis implies the controlled spatial organization of cells that gives rise to tissues and organs in early embryonic development. While morphogenesis is under strict genetic control, the formation of specialized biological structures of specific shape hinges on physical processes. Tissue engineering (TE) aims at reproducing morphogenesis in the laboratory, i.e., in vitro, to fabricate re...
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In cancer, proteoglycans have been found to play roles in facilitating the actions of growth factors, and effecting matrix invasion and remodeling. However, little is known regarding the genetic and functional importance of glycan chains displayed by proteoglycans on dendritic cells (DCs) in cancer immunity. In lung carcinoma, among other solid tumors, tumor-associated DCs play largely subversi...
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ژورنال
عنوان ژورنال: Cell Chemical Biology
سال: 2016
ISSN: 2451-9456
DOI: 10.1016/j.chembiol.2015.12.007